A study published in BMCMedicine finds that that people with poor sleep have an increased risk of cardiovascular heart disease. This is especially pronounced in people with sleep-related breathing disorders.
]. In brief, more than half a million participants aged 40 to 69 provided informed consent to enrolment and data linkage to electronic health records. The baseline assessment included self-reported questionnaires, a computer-assisted personal interview, physical examinations, and biological sampling. The UK Biobank keeps removing all records of dropping out participants, so retrieving loss of follow-up is inapplicable.
Primary care data on clinical events and prescriptions covered 227,834 participants. Primary care clinical events were coded with Read codes version 2 or Clinical Terms Version 3 , while prescriptions were mainly coded with Read v2, British National Formulary , or Dictionary of Medicines and Devices .
: Method S2 and Fig. S1-2. The primary care was censored to September 2018, with data availability varied between participants and was determined by the registration date with a primary care practice.We identified the incidence of hospital inpatient disease events based on ICD-9 and ICD-10: CVD [
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