Researchers investigated whether Tongxinluo, a Chinese medicinal compound, could improve clinical outcomes among ST-segment elevation myocardial infarction patients.
By Pooja Toshniwal PahariaOct 26 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in JAMA, researchers investigated whether Tongxinluo, a Chinese medicinal compound, could improve clinical outcomes among ST-segment elevation myocardial infarction patients.
About the study In the present study, researchers evaluated the impact of Tongxinluo use by STEMI patients treated with STEMI guideline-directed medications such as coronary reperfusion and dual antiplatelet treatment. The primary study endpoint was one-month majorly adverse cardiovascular or cerebrovascular events , the composite measure of myocardial reinfarction, cardiac mortality, stroke, and emergent coronary artery revascularization. MACCE follow-ups were conducted every three to 12 months.
The team excluded individuals with severe STEMI complications, including mechanical complications, serious cardiogenic shock unresponsive to vasopressors, uncontrolled acute left-sided cardiac failure or pulmonary edema, and malignant arrhythmias that could not be controlled by anti-arrhythmic agents.
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