A new study from Veterans Affairs showed a higher death rate among COVID-19 patients who were given hydroxychloroquine. Dr. Christopher Plowe, a world-renowned malaria expert, says it's time to put the prescriptions on pause.
, to be clear, was conducted on a small sample size and has yet to be peer-reviewed. But its results echo anecdotal evidence that has been building about the dangers of the drug. In it, researchers analyzed the medical records of 368 male patients with COVID-19 from March 9 to April 11, at which point the men had either been discharged or had died. Researchers found that the death rate of those who were not given the drug was 11.
“An association of increased overall mortality was identified in patients treated with hydroxychloroquine alone,” the authors write. “These findings highlight the importance of awaiting the results of ongoing prospective, randomized, controlled studies before widespread adoption of these drugs.” Dr. Chrisopher Plowe, a professor of global health at Duke University and a world-renowned expert on malaria drugs , has been cautioning about prescribing the drug for weeks, telling Yahoo Life in an April 7 interview that “really serious cardiac issues,” including “potentially fatal cardiac arrhythmias,” can occur even with the first dose of the drug. Now, in the wake of new evidence, he talked to Yahoo Life about how the medical world should respond.Let’s start with the study itself.
This is another piece of evidence that I would say goes beyond anecdotal. This makes it all that much more clear — as it’s been pretty clear to some of us all along — that unless and until we have a proper randomized clinical trial, we’re speculating and going on our hunches. And that’s not a good way to decide how to treat people with a potentially fatal disease like COVID-19. We have to be very clear this doesn’t prove that these drugs have caused these deaths.
I do. I think the responsible thing would be to put out a very clear and unequivocal message that hydroxychloroquine may be dangerous and may increase the risk of death, and that those very optimistic, hopeful exhortations and comments should be walked back — not just from the White House, but from quite a few other public figures who’ve been making those statements.I fervently hope that the clinical trials show there is a benefit in at least some patients ...
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