How to turn evidence into policy in resource-limited settings. World View from Patti Gravitt, NCIGlobalHealth, as part of our series Rethinking Evidence in Medicine.
Beginning in the 1990s, evidence accumulated to show that infection with specific high-risk genotypes of human papillomavirus was a necessary but insufficient cause of invasive cervical cancer. Within a decade, this evidence was translated into HPV immunization and high-risk HPV-based screening.
A vast international effort ensured that these new HPV-based strategies could be implemented in resource-constrained as well as high-resource settings, so that global disparities could be reduced or eliminated. Unfortunately, these interventions have been slow to translate. HPV immunization and screening remain unacceptably low in countries with the highest burden.
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