Higher Mortality Risk in Individuals with Severe Mental Illness Following COVID-19

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Higher Mortality Risk in Individuals with Severe Mental Illness Following COVID-19
COVID-19Severe Mental IllnessMortality Risk
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A recent study examines the mortality risk in individuals with severe mental illness (SMI) after contracting COVID-19. The study also explores the impact of multimorbidity and ethnicity/race on this risk.

By Tarun Sai LomteOct 31 2023Reviewed by James Ducker In a recent study published in the British Journal of Psychiatry, researchers evaluated mortality in individuals with severe mental illness following coronavirus disease 2019 infection.

Exploring the determinant factors of post-COVID-19 mortality In the present study, researchers investigated whether mortality risk was higher in people with SMI post-COVID-19 and whether multimorbidity and ethnicity/race had any effect on this risk. Data from family practices in Northern Ireland and England were obtained from the Aurum database. Patients in this database broadly represented the United Kingdom population by age, sex, area-level deprivation, and geographical distribution.

Data on admission to intensive care unit , multimorbidity linked with higher COVID-19 risk, and corticosteroid drug and immunological therapy were also included. Clinical variables included body mass index and smoking status. Multivariable Cox proportional hazards regression was used to estimate differences in mortality between SMI and control groups.

Patients in the SMI group were at a higher risk of all-cause mortality in gender- and age-adjusted models, which was consistent in models with further adjustment for smoking status, BMI, area deprivation, multimorbidity, and ethnicity/race. There were no interactions between ethnicity/race and SMI.

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COVID-19 Severe Mental Illness Mortality Risk Multimorbidity Ethnicity Race

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