High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects
We thank M.-m. Poo for helpful discussions and insightful comments on this manuscript; H. Yang and B. Wang from Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, for helpful discussions and technical assistance; L.-L. Chen from CAS Center for Excellence in Molecular Cell Science for the gift of the RanCas13b and dRanCas13b plasmids; and Y. Wang, Y. Zhang and Q. Hu from the Optical Imaging facility and S. Qian, H. Wu and L.
Jia Huang, Qingquan Xiao, Bingbing He, Xue Dong, Yuanhua Liu, Dingyi Han, Zikang Wang, Xuchen Wang, Wenqin Ying, Runze Zhang, Yu Wei, Chunlong Xu, Yingsi Zhou, Minqing Cai, Qifang Wang, Mingxing Xue, Guoling Li, Kailun Fang, Hainan Zhang & Hui YangJia Huang, Qingquan Xiao, Dingyi Han, Xuchen Wang, Runze Zhang & Yu Wei
Key Laboratory of Stem Cell Engineering and Regenerative Medicine of Fujian Provincial Colleges and Universities, Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, ChinaShanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai, ChinaZhoupu Hospital Affiliated to Shanghai Health Medical College and Shanghai Key Laboratory of MolecularImaging, Shanghai,...
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