Healthy Mice Created From 2 Fathers in Radical Gene-Editing Breakthrough

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Healthy Mice Created From 2 Fathers in Radical Gene-Editing Breakthrough
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Scientists claim they have created mice with two fathers in a breakthrough that could someday be replicated in humans.

from Osaka University told the Human Genome Editing conference on Wednesday that he achieved the breakthrough after changing the chromosomes in a male cell from XY to XX.

He then used that technique to make female eggs, called oocytes, from male cells and fertilized them to create seven mice with two biological dads. The discovery has yet to be validated by a review of scientific peers and is still in the early stages of development. Still, if it is confirmed, it raises the prospect of male couples someday having their own biological children.Cells are pliable, and with the right prompts, scientists have learned to make them change from one type of cell to another.

To make the egg, the scientists used male skin cells with X and Y chromosomes and reprogrammed them so they would turn into so-called pluripotentThey then deleted the Y chromosomes in the cells and duplicated the cells' X chromosomes, before prompting the cells to turn into egg cells with two X chromosomes.."We really tried to establish a system to duplicate the X chromosome.

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