Gilead's remdesivir shows modest improvement in moderate COVID-19 patients

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Gilead's remdesivir shows modest improvement in moderate COVID-19 patients
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Gilead Sciences Inc on Monday reported that its antiviral drug remdesivir provided a modest benefit in patients with moderate COVID-19 given a five-day course of the treatment, while those who received the medicine for 10 days in the study did not fare as well.

) on Monday reported that its antiviral drug remdesivir provided a modest benefit in patients with moderate COVID-19 given a five-day course of the treatment, while those who received the medicine for 10 days in the study did not fare as well.

At day 11, around 76% of the patients in the 5-day treatment group showed improvement in clinical status versus 66% for standard care alone, Gilead said. Remdesivir is being closely watched after the U.S. Food and Drug Administration granted emergency use authorization last month, citing results from a U.S. government study that showed the drug reduced hospitalization stays by 31%, or about four days, compared to a placebo.

The drug has received approval by Japanese health regulators. U.S. approval requires a rigorous, time consuming FDA review, but EUAs can be used in a health crisis when other options are not available.The drug, which previously failed as a treatment for Ebola, is designed to disable the mechanism by which certain viruses, including the new coronavirus, make copies of themselves and potentially overwhelm their host’s immune system.

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