Neurodegenerative diseases like Alzheimer's and Parkinson's can be associated to depression and anxiety. Dr. Sabine Krabbe, a neuroscientist at DZNE's Bonn site, is receiving 1.2 million US dollars from the Chan Zuckerberg Initiative to understand the mechanisms involved in the onset of these syndromes.
Nov 10 2023DZNE - German Center for Neurodegenerative Diseases Neurodegenerative diseases like Alzheimer's and Parkinson's can be associated to depression and anxiety. Dr. Sabine Krabbe, a neuroscientist at DZNE's Bonn site, is receiving 1.2 million US dollars from the Chan Zuckerberg Initiative to understand the mechanisms involved in the onset of these syndromes.
Spotlight on the emotion center At a microscopic level, diseases such as Alzheimer's and Parkinson's have especially one thing in common that might be related to psychiatric problems: protein deposits in the amygdala, the brain region that is particularly involved in controlling emotions. Hence it is sometimes called the brain's "emotion center".
Cellular precision The behavioral experiments are complemented by microscopic measurements of the activity of neural networks and even individual cells. For this, Krabbe and her team are using miniature microscopes weighing less than two grams. "A mouse can wear such a device on its head without any problems, while it moves around freely. We record what the animal is doing at a particular time and what is happening simultaneously in the amygdala.
Neurodegenerative Diseases Alzheimer's Parkinson's Depression Anxiety Funding Research Neuroscience Mental Health
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