From Neanderthal genome to Nobel prize: meet geneticist Svante Pääbo

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From Neanderthal genome to Nobel prize: meet geneticist Svante Pääbo
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Nature asked the pioneer of ancient-DNA research about some of his greatest discoveries.

about plans to engineer Neanderthal-like tissues and how he ended up being hurled into a pond to celebrate winning his Nobel prize.It’s a tradition at our institute that you throw PhD candidates into the pond when they pass their exams. And some people had the idea that it would be appropriate to throw me into the pond. It was the second time, actually — there has been one crazy party before where that happened. But that’s a long time ago. I hope this is the last time I end up in the pond.

Svante Pääbo celebrates his Nobel Prize according to tradition at the the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.As a kid, I always wanted to be an archaeologist or Egyptologist. And then I started studying that at university. But I had much too romantic ideas about what it would be like. I ended up studying medicine and molecular biology.

Your field went through a crisis in the 1990s and 2000s, when a lot of ancient-DNA findings were affected by contamination. Was that difficult?turned out to have been contamination from a present-day human. And then people started getting DNA from dinosaurs and inclusions in amber, things like that. That was when everyone felt that we needed more-stringent controls, and — when there are extraordinary claims — that things should be reproduced in a second laboratory.

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