Estrogen levels may make alcohol more rewarding to females, say authors of study on binge-drinking mice

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Estrogen levels may make alcohol more rewarding to females, say authors of study on binge-drinking mice
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Findings may mean women drink to excess during certain points in their menstrual cycle.

In their second set of experiments, the scientists injected female and male mice with viruses that reduce the levels of estrogen receptors into the. The mice were then encouraged to drink to the extent that their blood alcohol levels reached those seen in binge-drinking humans, as defined by the U.S.The team found that a specific type of receptor enabled estrogen to boost how dopamine neurons responded to alcohol. This may make drinking seem more rewarding in females.

She said the research suggests there are different brain mechanisms involved in binge drinking in males and females, and this is important when considering treatments for alcohol use disorder. Targeting estrogen receptors is one option, but drugs that do this have side effects that would outweigh the benefits in healthy women, Lasek said. She hopes future studies will help her team find a targeted approach without negative side effects.

Women may be more prone to drinking alcohol to excess during this time because they find it more rewarding, and there is some evidence that this is the case, said. This could put women at greater risk of developing alcohol-related health issues, including drinking problems, she said.In the U.S., around 9.2 million men and 5.3 million women struggle with alcohol use disorder.

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