Efficacy and safety of monoclonal antibodies against SARS-CoV-2 during pregnancy Monoclonal Antibodies Efficacy Pregnancy SARSCoV2 Coronavirus Disease COVID tandfonline UninaIT
Editorial: Safety and efficacy of monoclonal antibodies anti SARS-CoV-2 in pregnancy. Image Credit: Naeblys / Shutterstock
Therapeutic management of pregnant women with COVID-19 In pregnant women, COVID-19 has been found to increase the risk of admission to the intensive care unit and mortality. The disease is also known to cause neonatal complications. Among available repurposed antiviral drugs, remdesivir is recommended for pregnant women with progressive COVID-19. Overall, this drug is safe and well-tolerated among pregnant women with COVID-19.
In overweight/obese pregnant women , treatment with monoclonal antibodies has been found to prevent COVID-19 progression and hospitalization. Another study involving 30 pregnant women with COVID-19 has described that treatment with monoclonal antibodies helps improve symptoms in 85% of the participants. Treatment-related adversities, including hypotension and dizziness, have been observed in only one participant.
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