Early Onset Colorectal Cancer: Why Is This Happening?

In this Q&A, experts discuss what we know and don't know about the rising rates of colorectal cancer in younger patients:

species, for instance, make toxins that may play a carcinogenic role in the lining of the colon.

Still, no large studies exist comparing the microbiome in young versus older-onset colorectal cancer. Most studies include patients 60 and older, and others that do compare younger and older patients show no statistically significant correlations between patient age and a particular bacterium. Some studies, however, do suggest that the microbiome varies with age, though we still need more research to understand why this change happens and how it affects CRC disease risk and course.

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