There are three reasons coffee and other caffeinated drinks can lead to fatigue
A doctor has explained why coffee and other caffeinated drinks, which people often have to feel more awake and alert, can actually have the opposite effect. Dr Mehmet Oz was talking to Dr Carol Ash on his TV show to discuss how coffee could be depleting your energy levels.
Adenosine is also responsible for creating pressure to sleep, and it controls the restorative deep sleep state. When caffeine binds to adenosine, it causes alertness, but it does not stop the production or build-up of adenosine. She said people are better off only having one or two cups of coffee per day to prevent you from developing a tolerance to caffeine, which would mean you need to consume more to get the same effects.
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