Bigger is better for genetic tests that check for cardiomyopathy, arrhythmias northwesternu JAMACardio
). For patients with multiple cardiomyopathy subtypes indicated, the diagnostic yield was 23 of 86 patients . Among 686 patients with an arrhythmia-specific diagnostic indication, 145 had a positive result, 355 had an uncertain result, and 186 had a negative or carrier result. Within the arrhythmia-specific diagnostic indications, long QT syndrome was associated with the highest yield , and catecholaminergic polymorphic ventricular tachycardia was associated with the lowest yield .
Cardiomyopathy indications with arrhythmia-consistent genetic test results comprised 12 of 75 gained diagnoses , and arrhythmia indications with cardiomyopathy-consistent genetic test results comprised 15 of 75 gained diagnoses . Among 689 patients with positive results and a specific diagnostic indication, 27 of 75 had an arrhythmia diagnosis but a positive test result for cardiomyopathy or vice versa.Among the 954 patients with a positive result, 306 had family members referred and tested.
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