Dementia risk is reduced by a Mediterranean diet Dementia Diet Genetic PublicHealth UKBiobank MedDiet MediterraneanDiet BMCMedicine UniofNewcastle UniofExeter EdinburghUni Deakin orebrouni Cambridge_Uni ohiou
By Suchandrima BhowmikMar 15 2023Reviewed by Danielle Ellis, B.Sc. Dementia prevention is a global public health priority due to the high societal cost of this condition. Dementia incidence can be reduced by identifying and targeting modifiable risk factors through personalized or public health interventions. One such risk factor is diet which can be targeted for dementia prevention and risk reduction.
Study: Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. Image Credit: Marian Weyo / Shutterstock Polygenic risk scores were used for the estimation of the genetic risk of dementia. All-cause incident dementia cases were confirmed using hospital inpatient records and death registries. The International Classification of Diseases coding system was used for recording the diagnoses. Sensitivity analyses were carried out to assess the robustness of associations between dementia incidence and MedDiet adherence.
Higher adherence to the MedDiet was reported to be associated with 4.2 to 6.9 percent lower dementia risk for the MEDAS continuous and PYRAMID scores. Additionally, a higher polygenic risk score was reported to be associated with greater dementia risk. The results from the sensitivity analysis also confirmed that higher MedDiet adherence was associated with lower dementia incidence.
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