DARPA works on a readily available blood substitute for trauma settings

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DARPA works on a readily available blood substitute for trauma settings
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The new blood is meant to sustain warfighters and civilian casualties in austere, pre-hospital settings.

Lack of readily available blood is the most common cause of potentially survivable death in trauma in both military and civilian settings. This is because whole blood is complicated to manage as it has limited viability, requires cold storage, and is not always available due to logistical challenges and donor dependence.Making things even more difficult is the fact that, to improve chances of survival in trauma settings, patients should have access to blood in 30 minutes or less.

They plan to do this by integrating multiple bio-artificial and synthetic components to deliver oxygen, stop bleeding, and replace volume—essential therapeutic functions of whole blood in resuscitation. They will evaluate efficacy and safety in increasingly complex and realistic trauma models and intend to develop strategies for stabilizing the product for months without cold storage and scalable manufacturing methods.

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