Pool testing won't deliver results more quickly, which remains a hurdle for labs struggling to keep pace in hotspot communities.
Public or academic health labs in California, Washington and Nebraska have used or gained approval for the testing method. And last weekend, Quest Diagnostics became the first commercial laboratory to get Food and Drug Administration authorization to conduct sample pooling. It’s part of the lab company’s effort to increase capacity to 150,000 tests each day by the end of July.
Peter Iwen, director of Nebraska Public Health Laboratory, began pooling in March because his lab faced a shortage of reagents. He received authorization from the governor after the state declared a state of emergency. Pooling is used to process molecular-based tests that require a nasal swab sample from an individual. The sample is placed in a liquid tube called transport media and sent to a lab. When the lab pools samples, it mixes the liquid samples from several tubes while separating a portion of the original sample. If the pooled sample tests positive, lab workers then test the individual samples to determine which patients have the virus.
" are trade-offs you have with every diagnostic test, really,” Maldonado said."If you’re screening large populations to go back to school, I think the broader, pool-based tests could work."Time, manpower and supplies "That’s where it stops being a resource save and it becomes a resource drain," Wroblewski said. "It takes more time. It takes more manpower and it takes more supplies."
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