Children's tonsils are major sites of prolonged SARS-CoV-2 infection ChildHealth Tonsils adenoids Children Coronavirus Disease COVID SARSCoV2 medrxivpreprint Unesp_Global
By Dr. Priyom Bose, Ph.D.Jan 29 2023Reviewed by Benedette Cuffari, M.Sc. The severe acute respiratory syndrome coronavirus-2 , the causal agent of the ongoing coronavirus disease 2019 pandemic, causes respiratory infection in people of all ages.
About the study The current cross-sectional study was conducted between October 2020 and September 2021 at the University of São Paulo. Children between the ages of three and 11 with recurrent tonsillitis or obstructive sleep apnea who underwent adenoidectomy or tonsillectomy were included in the study.
About 50% of the patients had no associated diseases; however, the other 50% of the cohort were previously diagnosed with allergic rhinitis, recurrent otitis media, or mild asthma. SARS-CoV-2 genetic material was detected using quantitative reverse transcription PCR in three samples from children with confirmed COVID-19. Since viral burden varied significantly from hundreds to thousands of copies per microgram of ribonucleic acid , the authors presumed that participants underwent a tonsillectomy at different times post-infection.
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