CDC to recommend antibiotic prophylaxis for bacterial STIs

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CDC to recommend antibiotic prophylaxis for bacterial STIs
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The Centers for Disease Control and Prevention is recommending the use of the antibiotic doxycycline as a preventive measure against bacterial sexually transmitted infections, or STIs.

The CDC on Monday published a notice for comment from physicians and public health officials on proposed guidance on the use of doxycycline as prophylaxis to prevent gonorrhea, chlamydia, and syphilis, which experts said could be a turning point in the fight against the STI epidemic.

"Novel approaches are needed to address the STI epidemic, especially for populations disproportionately affected," the CDC said in its proposed guidance. There are higher rates of STIs among men who have sex with men, with repeated bacterial infections being a possible indicator of undiagnosed HIV infection. The CDC already recommends that nonmonogamous men who have sex with men seek testing for STIs at three- to six-month intervals, depending on their sexual behavior.

Another reason for limiting this recommendation to men who have sex with men is the risk of widespread use contributing to antibiotic resistance or mutations in bacteria that make prevention and treatment more difficult over time. Antibiotic resistance is one greatest global public health threats, according to the World Health Organization.

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