Carbon Quantum Dots Protect Against Neuronal Cell Death: ACSChemNeurosci UTEP haverfordedu carbon nanomaterials quantumdots nanomedicine neuroscience
By Surbhi JainAug 15 2022Reviewed by Susha Cheriyedath, M.Sc. In an article recently published in the journal ACS Chemical Neuroscience, researchers discussed the attenuation of paraquat -induced neuronal compromise in vitro and in vivo by carbon quantum dots derived from citric acid .
Applications of PQ in the Treatment of Neurodegenerative Diseases The agricultural and xenobiotic agent PQ, which is used as a herbicide in the cultivation of crucial crops, including soy, corn, and cotton, is of particular relevance. A rising range of neurodegenerative disorders, including Parkinson's disease , has been related to research on PQ.
Utility of Citric Acid-Sourced Carbon Quantum Dots In this study, the authors assessed the neuroprotective effects of citric acid-sourced carbon quantum dots on PQ-insulted human neuroblastoma-derived SHSY5Y cell lines and on a nematode that had been exposed to paraquat . According to the study, Cit-carbon quantum dots were a potentially useful bio-based nanomaterial that can be produced using green chemistry to treat neurodegenerative diseases.
Neuroprotective Effects of Cit-Sourced Carbon Quantum Dots The size of the Cit-CQDs ranged from 10 to 60 nanometers. A wide peak in the ultraviolet –visible spectrum at 330 nanometers indicated the presence of conjugated moieties capable of photoluminescence. The presence of oxidized groups and conjugated centers , which validated the solubility and photoluminescence capabilities of Cit-CQDs, was demonstrated by the infrared spectrum.
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