The Callisto Protocol's Contagion Bundle arrives in a few days time.
If you haven't had your fill of seeing all the many weird and wonderful ways that protagonist Jacob Lee can, I have good news. The game's upcoming Contagion Bundle will add 14 new ways for this to happen. Sorry Jacob!
As previously announced, The Callisto Protocol's Contagion Bundle will add a permadeath mode to the game when it releases on 14th March. It will also see the addition of the Watchtower Skin Collection. In the meantime, if you are yet to experience all of the death animations that came with The Callisto Protocol's launch, you can check out Zoe's extensive video cataloguing them below. May I recommend finding a cushion to hide behind before hitting play.This is not the first new content to come to The Callisto Protocol. Back in January, a
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Control heads up all-women Humble charity bundleMarch's latest bundle will see proceeds go towards charities Girls Make Games Scholarship Fund and Girls who Code.
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Microsoft calls time on RPS for Exchange OnlineRemote PowerShell Protocol users must shift into PowerShell v3 module
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UNet and MobileNet CNN-based model observers for CT protocol optimization: comparative performance evaluation by means of phantom CT imagesThe Journal of Medical Imaging (JMI) allows for the peer-reviewed communication and archiving of fundamental and translational research, as well as applications, focused on medical imaging, a field that continues to benefit from technological improvements and yield biomedical advancements in the early detection, diagnostics, and therapy of disease as well as in the understanding of normal conditions.
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Associations between mortality from COVID-19 and other causes: A state-level analysisBackground During the COVID-19 pandemic, the high death toll from COVID-19 was accompanied by a rise in mortality from other causes of death. The objective of this study was to identify the relationship between mortality from COVID-19 and changes in mortality from specific causes of death by exploiting spatial variation in these relationships across US states. Methods We use cause-specific mortality data from CDC Wonder and population estimates from the US Census Bureau to examine relationships at the state level between mortality from COVID-19 and changes in mortality from other causes of death. We calculate age-standardized death rates (ASDR) for three age groups, nine underlying causes of death, and all 50 states and the District of Columbia between the first full year of the pandemic (March 2020-February 2021) and the year prior (March 2019-February 2020). We then estimate the relationship between changes in cause-specific ASDR and COVID-19 ASDR using linear regression analysis weighted by the size of the state’s population. Results We estimate that causes of death other than COVID-19 represent 19.6% of the total mortality burden associated with COVID-19 during the first year of the COVID-19 pandemic. At ages 25+, circulatory disease accounted for 51.3% of this burden while dementia (16.4%), other respiratory diseases (12.4%), influenza/pneumonia (8.7%) and diabetes (8.6%) also contribute. In contrast, there was an inverse association across states between COVID-19 death rates and changes in death rates from cancer. We found no state-level association between COVID-19 mortality and rising mortality from external causes. Conclusions States with unusually high death rates from COVID-19 experienced an even larger mortality burden than implied by those rates alone. Circulatory disease served as the most important route through which COVID-19 mortality affected death rates from other causes of death. Dementia and other respiratory diseases made the second and third l
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The Effect of a Hydroxytyrosol-Rich, Olive-Derived Phytocomplex on Aerobic Exercise and Acute RecoveryThere is current scientific interest in naturally sourced phenolic compounds and their potential benefits to health, as well as the effective role polyphenols may provide in an exercise setting. This study investigated the chronic effects of supplementation with a biodynamic and organic olive fruit water phytocomplex (OliPhenolia® [OliP]), rich in hydroxytyrosol (HT), on submaximal and exhaustive exercise performance and respiratory markers of recovery. Twenty-nine recreationally active participants (42 ± 2 yrs; 71.1 ± 2.1 kg; 1.76 ± 0.02 m) consumed 2 × 28 mL&8729;d−1 of OliP or a taste- and appearance-matched placebo (PL) over 16 consecutive days. Participants completed a demanding, aerobic exercise protocol at ~75% maximal oxygen uptake (V&729;O2max) for 65 min 24 h before sub- and maximal performance exercise tests prior to and following the 16-day consumption period. OliP reduced the time constant (τ) (p=0.005) at the onset of exercise, running economy (p=0.015) at lactate threshold 1 (LT1), as well as the rating of perceived exertion (p=0.003) at lactate turnpoint (LT2). Additionally, OliP led to modest improvements in acute recovery based upon a shorter time to achieve 50% of the end of exercise V&729;O2 value (p=0.02). Whilst OliP increased time to exhaustion (+4.1 ± 1.8%), this was not significantly different to PL (p > 0.05). Phenolic compounds present in OliP, including HT and related metabolites, may provide benefits for aerobic exercise and acute recovery in recreationally active individuals. Further research is needed to determine whether dose-response or adjunct use of OliP alongside longer-term training programs can further modulate exercise-associated adaptations in recreationally active individuals, or indeed support athletic performance.
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