If humans are ever to journey to Mars they will need ways to keep their bones strong in space – lettuce genetically engineered to produce a hormone that boosts bone formation might help.
at the University of California, Davis, and his colleagues used a soil bacterium to transfer a gene that produces a variant of the human version of parathyroid hormone into lettuce. The same variant is commonly used as a drug to stimulate bone formation. The researchers screened a number of modified lettuce plants and observed that the most productive specimens produced 10 to 12 milligrams of PTH per kilogram.
“This is a new way of thinking and solving problems for space exploration,” says Yates. “Typically in the past it’s been abiotic solutions – just package stuff up and fly it with you or have consumables that you use up and have more sent to you from Earth.” Yates also speculates the lettuce could be used to treat osteoporosis on Earth too, where the condition is seen in millions of people.at the University of Aberdeen, UK. But the use of a hormone that builds up tissue like PTH might be unnecessary, he adds. “You can usually, unless it’s very profound, get away with other drugs which prevent bone breakdown, rather than a bone-forming drug.”
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