Bringing along their own ANP32 proteins may give avian flu viruses a jump-start on copying themselves to adapt to and infect humans and other animals.
Viruses usually infect only certain types of hosts. For instance, many viruses that infect humans don’t infect other animals. But influenza viruses often seem to jump from birds to other species. In 2009, the). No one knows whether that flu virus may eventually infect people and, if it does, whether it will have the ability to spread easily and cause a pandemic.
The finding may help researchers better understand and predict which flu viruses have the potential to cause a pandemic. “Today’s flu virus needs this help in order to replicate itself fast enough inside any host cell so that it doesn’t get clobbered by our immune response and shut down,” says Barclay, who was not involved in the work.
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