Are Breakthrough Cases Being Reported With Bivalent COVID Booster? Top Doc Says Yes
"It's good news that we haven't had a new variant of concern... But still, every single one of those new subvariants is outcompeting the old one, meaning it is more infectious, more contagious, and potentially can carry other, you know, other issues with it," Arwady said.
Officials say that the new strain is most prevalent in the western United States, making up more than 6% of cases in an area that includes Arizona, California, Hawaii and Nevada. Arwady noted that hospitalizations related to COVID are on the rise, leading the city to be listed under an elevated community level for the virus, per CDC standards.
The fact that subvariants remain under the omicron umbrella has so far led experts to believe the new bivalent booster, which was specifically designed to target the omicron variant and the BA.5 subvariant, will continue to provide protection. "We are pleased to see that both of our bivalent booster vaccine candidates offer superior protection against Omicron BA.4/BA.5 variants compared to our original booster, which is encouraging given COVID-19 remains a leading cause of hospitalization and death globally. In addition, the superior response against Omicron persisted for at least three months after the mRNA-1273.214 booster," Stéphane Bancel, Moderna's chief executive officer, said in a statement.
"I think it's very good news that the bivalent booster is working sort of like we thought it would," Arwady said."That it would help generate antibodies not just for the BA.4 or [BA.5], but specifically for subvariants that continue to emerge. That's what we expected. We didn't know for sure, but the real world data is behaving like the hypothesis suggested."
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