A new study published today in the American Journal of Infection Control (AJIC) reveals that the use of doxycycline may help protect against Clostridioides difficile (C. diff) infection for some patients with pneumonia.
) reveals that the use of doxycycline may help protect against Clostridioides difficile infection for some patients with pneumonia.who had experienced C. diff infections in the prior year, the use of doxycycline, instead of the more commonly used azithromycin, reduced the development of new C. diff infections by 45%., C. diff infections can be deadly. There are more than 450,000 C. diff infections in the U.S. each year, leading to as many as 30,000 deaths, according to public health estimates.
As expected, based on clinical guidelines, most patients were treated with azithromycin while a small proportion received doxycycline . Overall, less than 1% of patients developed C. diff infections, but among patients who had experienced a C. diff infection in the year before their pneumonia diagnosis, 12% developed a new C. diff infection associated with the antibiotic treatment.
Of the 1,234 patients who developed C. diff infections within 30 days, 1,104 of them had no prior history of C. diff.
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