Air pollution lowers COVID-19 vaccine immune response AirPollution ImmuneResponse Pollution Vaccine Coronavirus Disease COVID ehponline ISGLOBALorg
Study: Long-Term Exposure to Air Pollution and COVID-19 Vaccine Antibody Response in a General Population Cohort . Image Credit: Toa55 / Shutterstock
Note that research on immunological responses to COVID-19 vaccines, similarly to other vaccines, has remained focused on IgG responses. However, in this study, researchers measured IgM antibodies elicited by vaccination in participants sampled within the first month after receiving the first dose. On the contrary, they analyzed the IgG/IgA levels of all participants regardless of sampling time post-vaccination.
Related StoriesLikewise, the team used linear regression models to examine the association between air pollution levels and the log10-transformed antibody levels and expressed results as the percentage change in the geometric mean and 95% confidence intervals . After continuously modeling air pollutants, the team also estimated and reported an interquartile range for each pollutant.
Moreover, the observed decrease lasted for many months in participants exposed to above-average air pollution levels. Furthermore, the authors observed this decrease in early responses , and late responses reflected as IgG levels.
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