A new study has used postmortem brain tissue to examine genomic differences in individuals with attention deficit hyperactivity disorder. A study led by researchers at the National Human Genome Research Institute, which is part of the National Institutes of Health, has identified differences in gen
The new study uses postmortem brain tissues to understand genomic differences in individuals with attention deficit hyperactivity disorder. Credit: Darry Leja, NHGRI
As one of the most common mental health conditions, ADHD affects about 1 in 10 children in the United States. Diagnosis often occurs during childhood, and symptoms may persist into adulthood. Individuals with ADHD may be hyperactive and have difficulty concentrating and controlling impulses, which may affect their ability to complete daily tasks and their ability to focus at school or work.
Importantly, the researchers found that these differences affected the expression of genes that code for neurotransmitters, which are chemicals that brain cells use to communicate with one another. In particular, the results revealed differences in gene expression for glutamate neurotransmitters, which are important for brain functions such as attention and learning.
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