Scientists uncover that a specific molecule found in broccoli interacts with a receptor in mice, resulting in improved gut health. Broccoli is widely recognized for its health benefits. For instance, studies have demonstrated that consuming more of this cruciferous vegetable can reduce the risk of
A recent study at Penn State revealed that broccoli contains molecules that bind to a receptor in mice, protecting the lining of the small intestine and inhibiting the development of disease. The findings strengthen the evidence for broccoli and other cruciferous vegetables as “superfoods” that promote gut health and overall well-being.
Broccoli is widely recognized for its health benefits. For instance, studies have demonstrated that consuming more of this cruciferous vegetable can reduce the risk of cancer and type 2 diabetes. Now, a recent investigation conducted atrevealed that broccoli contains specific molecules that attach to a receptor in mice, safeguarding the small intestine lining and preventing disease progression. These results further reinforce the notion that broccoli truly is a “superfood.
According to Perdew, the wall of the small intestine allows beneficial water and nutrients to pass into the body but prevents food particles and bacteria that could cause harm. Certain cells that line the intestine — including enterocytes, which absorb water and nutrients; goblet cells, which secrete a protective layer of mucus on the intestinal wall; and Paneth cells, which secrete lysosomes that contain digestive enzymes — help to modulate this activity and keep a healthy balance.
The team found that mice that were not fed broccoli lacked AHR activity, which resulted in altered intestinal barrier function, reduced transit time of food in the small intestine, decreased number of goblet cells and protective mucus, decreased Paneth cells and lysosome production, and decreased number of enterocyte cells.
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