A Scientist's Pink Cast Leads To Discovery About How The Brain Responds To Disability

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A Scientist's Pink Cast Leads To Discovery About How The Brain Responds To Disability
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A neurologist put his healthy arm in a cast for two weeks to see how quickly the human brain can change after an injury or illness. The study suggests it's possible to reverse brain changes caused by disuse of a limb after a stroke or brain injury.

Nico Dosenbach decided to put his healthy arm in a cast to figure out more about how the brain deals with an immobilized limb.Tim Parker/Washington University School of Medicine

Dosenbach, an assistant professor at Washington University School of Medicine in St. Louis, repeated the experiment on two colleagues and got the same result. In all three people, the disconnected brain circuits quickly reconnected after the cast was removed., shows that"within a few days, we can rearrange some of the most fundamental, most basic functional relationships of the brain," Dosenbach says.

The discovery of the pulses that maintain unused motor circuits should allay some fears about using CIMT on children, Gauthier says."Therapists have expressed concern [about] what's going to happen if you restrain that stronger arm for two weeks," she says."Is that going to affect their normal development? And what this study shows is that it probably won't.

Dosenbach agreed, and chose a pink cast because"my daughter at the time was two and I didn't want to frighten her." He quickly got better at these daily tasks."The whole goal was that I wouldn't cut myself any slack, and so, yeah, I got pretty good at changing diapers with a fiberglass cast on," he says.He says those scans revealed dramatic changes in the first few days.

"We start seeing in the disused motor circuitry these pulses of spontaneous activity that are very large that actually seem to maintain the connection," he says, adding that this would explain how people are able to regain motor skills very quickly after an injured arm or hand has healed.

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