The discovery could benefit millions of people worldwide. A new discovery could be a game-changer for patients with type 2 diabetes. Researchers at the Diabetes, Obesity, and Metabolism Institute (DOMI) at the Icahn School of Medicine at Mount Sinai have discovered a therapeutic target for the pres
The researchers discovered a therapeutic target for beta cell preservation and regeneration.A new discovery could be a game-changer for patients with type 2 diabetes. Researchers at the Diabetes, Obesity, and Metabolism Institute at thehave discovered a therapeutic target for the preservation and regeneration of beta cells , the cells in the pancreas that produce and distribute insulin. The finding could also help millions of individuals throughout the globe by preventing insulin resistance.
The research team found that it was possible to counteract the effects of ChREBPβ and the β-cell death they observed by increasing expression of an alternate form of the protein, ChREBP⍺, or by activating nuclear factor-erythroid factor 2 —a protein that protects cells from oxidative damage—in mice and human β cells, thus preserving β-cell mass.
“Moreover, we found that if you remove ChREBPβ or counteract it pharmacologically, you can mitigate the effects of glucose toxicity and protect those cells. This exciting discovery creates an opportunity to develop therapeutic agents that target this molecular mechanism, effectively block ChREBPβ production, and thus preserve β-cell mass.
日本 最新ニュース, 日本 見出し
Similar News:他のニュース ソースから収集した、これに似たニュース記事を読むこともできます。
How ‘Street Fighter 6’ brings back the spirit of the arcadesThe Battle Hub in the closed beta showed a metaverse-type potential for the upcoming Capcom fighting game
続きを読む »
FDA authorizes Omicron-specific boosters for kids as young as 5The Food and Drug Administration on Wednesday authorized updated COVID-19 boosters for children between the ages of 5-11.
続きを読む »
Video games could trigger deadly heart problems in children, study findsAustralian researchers found that war-type video games were the main trigger that caused heart issues in kids.
続きを読む »
Ubisoft's 'Project U' Footage Leaks Online Ahead of RevealInformation about a new game in development from Ubisoft has leaked online. The game has been [...]
続きを読む »
‘Dungeons & Dragons’ Documentary in the Works at HasbroThe project is one of many films, scripted and unscripted TV series, and new games to come from the Entertainment One owner based on the 50-year-old tabletop roleplaying game.
続きを読む »
Elon Musk jumps on new weight-loss trend: diabetic medicationsMany people, including buisness magnate Elon Musk, have used a drug known as Wegovy to shed some weight or jumpstart their weight loss. Although it can be pricy.
続きを読む »