Naked mole rats are well known for living far longer lives than any rodent ought to have.
The naked mole rat gene increased median and maximum lifespan in mice, shown by the red line.
"Our study provides a proof of principle that unique longevity mechanisms that evolved in long-lived mammalian species can be exported to improve the lifespans of other mammals,"Naked mole rats really are extraordinary: they can live to more than 40 years old, whereas the mice in this study typically lived for 3 to 4 years.
might be achieved in humans. There are a variety of possible approaches for both increasing the production of HMW-HA and making sure it lasts longer in the body.scientists have tried to copy the genetic instructions in naked mole rats to improve human health – and if they manage to get it right in the years ahead, we may be able to borrow some of the biological codes to longevity and disease resistance. That's going to take time, however.
"It took us 10 years from the discovery of HMW-HA in the naked mole rat to showing that HMW-HA improves health in mice,"
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