Potent immune molecule could be used to treat COVID-19 and infections caused by viruses related to SARS-CoV-2.
Particles of SARS-CoV-2 bud from a cell. The virus and related pathogens are inhibited by an antibody culled from a person who had COVID-19. Credit: Steve Gschmeissner/Science Photo Library
A newly isolated antibody that blocks SARS-CoV-2 from infecting cells could one day be used to treat infections caused by current and future variants of the virus that causes COVID-19, and even infections from related virusesDavid Veesler and his colleagues at the University of Washington, Seattle, searched the blood of an infected person for antibodies that bind the SARS-CoV-2 spike protein, which lets the virus enter human cells.
S2K146 also binds spike protein from the two related viruses: SARS-CoV, which caused an outbreak of respiratory disease in 2002–2003, and WIV-1, which infects bats and has the potential to infect humans. Administering S2K146 to hamsters infected with SARS-CoV-2 greatly reduced or eliminated viral replication.
The team found that mutations that prevented S2K146 from binding to spike protein also rendered SARS-CoV-2 much less effective at infecting cells. This suggests that the virus is unlikely to mutate its way out of S2K146’s grasp.
日本 最新ニュース, 日本 見出し
Similar News:他のニュース ソースから収集した、これに似たニュース記事を読むこともできます。
Covid-19 news: Ministers plan for UK to ‘live with covid’Today’s covid-19 news: · UK ministers plan for nation to ‘live with covid’ · Novak Djokovic released from detention, but may have Australia visa cancelled · Mixed signals as to whether free lateral flow tests will be phased out in England
続きを読む »
Balancing COVID-19 health precautions for childrenDr. Grace Lee, pediatric infectious diseases physician at Stanford Children's Health, says we have to learn to live with COVID, but in a safe way. Transmission at schools are not as common as within the community, she says. Finally, getting kids vaccinated adds an important layer of protection to keep kids safe and to prevent the spread of the disease.
続きを読む »
Marin schools shuffle staff to cover COVID-19 teacher quarantinesKeeping schools open remains “top priority” for county public health and education teams as 3.6% of returned tests for students, staffers come back positive for coronavirus.
続きを読む »
Avacta pauses sales of COVID-19 antigen test to boost Omicron sensitivityBritish biotech firm Avacta Group said on Monday it was halting sales of its COVID-19 antigen lateral flow test, AffiDX, to replace antibodies in the device and boost its ability to detect the Omicron coronavirus variant at lower viral loads.
続きを読む »
Novartis to seek FDA approval for COVID-19 treatment after positive dataNovartis AG and Molecular Partners AG on Monday reported positive topline data from their antiviral Covid-19 treatment ensovibep, and will seek expedited...
続きを読む »