The endocannabinoid system that helps cannabis get us high is also vital to many other aspects of our health. Now we’re finally starting to understand why – and what that means for devising new treatments
The discovery of cannabis’s principal active ingredient is the stuff of scientific legend. In the early 1960s, a scientist in Israel named Raphael Mechoulam obtained some high-quality hashish from the police, who had confiscated the stash from smugglers. He isolated the components and then tested their effects, one by one, on monkeys in his lab.
Mechoulam, who died in March of this year, knew he had found his target as soon as he administered tetrahydrocannabinol, commonly known as THC. “It …
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