First human challenge study of Covid-19 yields valuable insights about how we get sick

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First human challenge study of Covid-19 yields valuable insights about how we get sick
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Challenge studies can be controversial because they involve intentionally giving someone a virus or other pathogen in order to study its effects on the human body.

That's just one of the findings from research that deliberately infected healthy volunteers with the SARS-CoV-2 virus. The findings were published Thursday in the journal Nature Medicine. Even with safeguards in place, there's an element of risk, particularly when studying a new virus.But they are also hugely valuable for understanding the course of an infection.

Dr. Kathryn Edwards, a pediatric infectious disease specialist at Vanderbilt University who wrote an editorial published alongside the study, said the research offers important information about infection and contagion with the SARS-CoV-2 virus.Blood and tissue samples collected for the study will continue to be analyzed for years to come, she said."I think those are all in the freezer, so to speak, and are being dissected. So I think that should be very powerful.

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