Taurine-Degrading Bacteria Influence Intestinal Microbiome A novel bacterium, Taurinivorans muris, which feeds on taurine and emits hydrogen sulfide, has been identified by researchers. This discovery offers valuable insights into gut health and lays the groundwork for future therapeutic interventi
, which exclusively consumes taurine and produces hydrogen sulfide. While hydrogen sulfide has protective properties against certain pathogens, excessive amounts can harm gut health. The discovery provides insight into the roles of taurine and hydrogen sulfide in the gut, as well as their broader health implications. The findings are integral to developing future microbiome-based therapies.
An international team of scientists led by microbiologist Alexander Loy from the University of Vienna has discovered a new intestinal microbe that feeds exclusively on taurine and produces the foul-smelling gas hydrogen sulfide. The researchers have thus provided another building block in the understanding of those microbial processes that have fascinating effects on health.
“The bacterium we described has a rather unbalanced diet,” explains Loy, “it specializes in consuming taurine.” Taurine is a semi-essential amino, which we synthesize in small amounts in our liver. However, we get most of our taurine from our diets – especially meat, dairy, and seafood.Like hydrogen sulfide, taurine is implicated in a smorgasbord of physiological processes.
“By isolating the first taurine degrader in the mouse gut, we’re one step closer to understanding how these gut microbes mediate animal and human health” explains Huimin Ye, lead author of the study.needs the help of other gut microbes to release it from bile acids. Taurine-containing bile acids are produced in the liver and are increasingly released into the intestine during a high-fat diet to help our body digest fats.
Reference: “Ecophysiology and interactions of a taurine-respiring bacterium in the mouse gut” by Huimin Ye, Sabrina Borusak, Claudia Eberl, Julia Krasenbrink, Anna S. Weiss, Song-Can Chen, Buck T. Hanson, Bela Hausmann, Craig W. Herbold, Manuel Pristner, Benjamin Zwirzitz, Benedikt Warth, Petra Pjevac, David Schleheck, Bärbel Stecher and Alexander Loy, 18 September 2023,
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